Panhypopituitarism may also develop in younger dogs due to a birth abnormality. Tumors can also affect other parts of the brain and even cause blindness. This is a reduction the in normal levels of many pituitary hormones. A condition called panhypopituitarism results. Most pituitary tumors are benign and slow growing, however, large tumors put pressure on the hypothalamus, the brain area next to the pituitary gland that regulates many important pituitary functions. Tumors are the most common cause of pituitary destruction in older dogs, but an injury or infection can also destroy tissue. Because it affects so much of the endocrine system, the pituitary gland is sometimes called the master gland. Many important hormones are produced here, including thyroid stimulatory hormone (TSH), adrenocorticotrophic hormone (ACTH), growth hormone (GH), and antidiuretic hormone (vasopressin). Despite its size, the pituitary gland produces a number of different hormones that regulate other endocrine glands and control many functions throughout the body. The pituitary gland is a small gland located at the base of the brain.
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